Medical Advisory Board

Dr-Bartels-medadv-pic-197x300Dr. Ute Bartels

Neuro-oncologist Dr. Ute Bartels is Associate Professor in the Paediatric Brain Tumour Program at the Hospital for Sick Children in Toronto.

She graduated from medical school at Johannes Wolfgang von Goethe University in Frankfurt, Germany.

Dr. Bartels first worked at the Children’s Hospital of the University in Mainz, Germany. There she finished her paediatric training and specialized in neonatology and paediatric haematology/oncology.

In 2002, she joined the Hospital for Sick Children in Toronto for a fellowship in paediatric neuro-oncology and became a staff physician in 2005. She was the acting section head of the program during the director’s sabbatical in 2007-2008.

Dr. Bartels received the Junior Faculty Award for Clinical Excellence in Paediatric Medical Care in 2009.

She completed a Master of Science in Clinical Epidemiology at the University of Toronto in 2010.

She was elected co-chairwoman of the European craniopharyngioma subgroup representing the field of oncology/endocrinology in 2011.

She is an active member of the Central Nervous System (CNS) Committee of the Children’s Oncology Group (COG) in North America and is a Principal Investigator of the impending CNS Germ Cell Tumour study.

She has numerous publications in her field of expertise including treatment of TSC associated subependymal giant cell astrocytoma (SEGA).

Dr-Major-clinic-pic-200x300Dr. Phillipe Major

Neurologist Dr. Philippe Major, Medical Advisor to TS Canada ST and Head of Canada’s first pediatric TSC Clinic at CHU Ste. Justine Hospital in Montreal.  The clinic was established in 2008 and has welcomed many TSC families from across Canada since then.

Dr Philippe Major finished his residency in Pediatric Neurology at the CHU Sainte-Justine in 2006. He then completed a fellowship in Pediatric Epilepsy at the Massachusetts General Hospital in 2008, where he was responsible for the Tuberous Sclerosis Complex (TSC) Clinic. He is now in charge of the first Canadian TSC clinic.

His research interests focus mainly on the characterization of the epileptogenicity and functional implications of malformations of cortical development, particularly those associated with TSC. He takes advantage of novel investigation tools such as the magnetoencephalography (MEG) and the diffusion tractography (DTI). He is also interested about the various clinical manifestations related to TSC, mostly to its neurological impacts (epilepsy, intellectual and developmental impairments, autistic spectrum disorder, and psychiatric involvement).

Dr-Pei-medadv-pic-207x300Dr. York Pei

Nephrologist Dr. Pei is a Professor of Medicine at the University of Toronto and a Staff Nephrologist at the Toronto General Hospital, University Health Network, where he currently directs a Hereditary Kidney Disease Clinic.

He obtained his research training in Clinical Epidemiology at McMaster University and later on, in Human Molecular Genetics in Toronto.

The major theme of his research program is to identify genetic factors involved in the initiation or progression of common kidney diseases, as potential targets for developing novel diagnostic tests and therapies.

His research focuses on genetic, genomic and translational research of several hereditary kidney disorders including autosomal dominant polycystic kidney disease, IgA nephropathy and idiopathic nephrotic syndrome, and is supported by grants from the Kidney Foundation of Canada, Physicians Incorporated Foundation, and Canadian Institutes of Health Research.

More recently, he has been involved as the site Principal Investigator for a randomized controlled trial of mTOR inhibitor in tuberous sclerosis complex.

He has published more than 90 peer-reviewed papers and has served on the Editorial Board for the Journal of American Society of Nephrology and Grant Review Panels for the Kidney Foundation of Canada, Canadian Institutes of Health Research, and National Institutes of Health, USA.

He is currently a member of the Scientific Advisory Committee for the Kidney Foundation of Canada and Polycystic Kidney Disease Foundation, USA.

Dr-Connolly-clinic-pic-255x300Dr. Mary Connolly

Neurologist Dr. Mary B Connolly, Medical Advisor to TS Canada ST since 2011 and Director of Canada’s second pediatric TSC Clinic in Vancouver at BC Children’s Hospital.  Dr. Connolly welcomes pediatric TSC patients at the clinic!

Dr. Mary Connolly, M.B.,B.Ch, FRCPC, FRCP(I), FRCP(Ed), Clinical Professor, Head Division of Pediatric Neurology, Children’s & Women’s Health Centre of British Columbia & University of British Columbia

To contact the TSC Clinic at BC Children’s Hospital, please make a referral with Neurology Department Assistant Nela Martic. 4480 Oak Street, Vancouver BC, V6H 3V4 Canada.  Tel 604 875 2975, Fax 604 875 2285.

“My research centers on various aspects of pediatric neurology, primarily epilepsy and surgical management of epilepsy.

Epilepsy is the most common chronic neurological disorder in children and is characterized by recurrent unprovoked seizures due to uncontrolled electrical activity in the brain. Thirty per cent or more of epilepsy cases do not respond to conventional epileptic medications. Other treatments for epilepsy are epilepsy surgery, vagus nerve stimulation, the ketogenic diet and investigational anti-epileptic drugs.

The epilepsy surgery program at BC Children’s Hospital was established in the mid 90s. My research focuses on outcomes following epilepsy surgery of various types and the influence of surgery on seizure control, quality of life, learning and attention. I am also involved in research in video-EEG monitoring, psychogenic non-epileptic seizures, psychiatric comorbidity in epilepsy and adverse reactions to anti-epileptic drugs.”

Dr-Franz-medadv-pic-200x300Dr. David Franz

Neurologist Dr. David Neal Franz is the Director of the Tuberous Sclerosis Clinic at Cincinnati Children’s Hospital Medical Center, which he established in 1993.

“For too long, the unique problems found in this disease have been lumped together with similar disorders, despite the fact that research has shown that disorders of the brain, heart, kidney, and other organs in tuberous sclerosis are quite different.”

David Neal Franz, MD, was born and raised in Dayton, Ohio. He received his undergraduate degree in history and literature from Earlham College in Richmond, Indiana.

After completing his training, he served as assistant professor of neurology and pediatrics at Wright State University before returning to Cincinnati Children’s Hospital Medical Center.

He established the Cincinnati Tuberous Sclerosis Clinic in 1993, to assist in the medical care of patients who have or are suspected of having tuberous sclerosis. The purpose of the clinic is not to replace care from the child’s pediatrician or family physician, but to assist the primary care physician in dealing with those aspects unique to tuberous sclerosis that affect the child’s health or development. The basis of the clinic is the realization that people with tuberous sclerosis are different from other individuals who have epilepsy, learning disabilities, behavior problems, etc.

For too long, the unique problems found in this disease have been lumped together with similar disorders, despite the fact that research has shown that disorders of the brain, heart, kidney, and other organs in tuberous sclerosis are quite different.

Photo courtesy of the Cincinnati Children’s Hospital Medical Center.